14/05 - 21:00
15/05 - 21:00
14/05 - 21:00
15/05 - 21:00
| 2021/05/23 | Feyenoord |  | 2-0 |  | FC Utrecht |
| Pts | SP | SG | U | N | T | GT | TD | PtsC | SPC | SGC | UC | NC | TC | GTC | PtsF | SPF | SGF | UF | NF | TF | GTF | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Ajax | 88 | 34 | 28 | 4 | 2 | 102 | 23 | +79 | 44 | 17 | 14 | 2 | 1 | 53 | 14 | 44 | 17 | 14 | 2 | 1 | 49 | 9 | a | ||
| 2 |  | PSV | 72 | 34 | 21 | 9 | 4 | 74 | 35 | +39 | 42 | 17 | 13 | 3 | 1 | 39 | 13 | 30 | 17 | 8 | 6 | 3 | 35 | 22 | a | ||
| 3 |  | AZ Alkmaar | 71 | 34 | 21 | 8 | 5 | 75 | 41 | +34 | 38 | 17 | 12 | 2 | 3 | 39 | 18 | 33 | 17 | 9 | 6 | 2 | 36 | 23 | a | ||
| 4 |  | Vitesse | 61 | 34 | 18 | 7 | 9 | 52 | 38 | +14 | 37 | 17 | 11 | 4 | 2 | 26 | 12 | 24 | 17 | 7 | 3 | 7 | 26 | 26 | a | ||
| 5 | | Feyenoord | 59 | 34 | 16 | 11 | 7 | 64 | 36 | +28 | 33 | 17 | 9 | 6 | 2 | 35 | 13 | 26 | 17 | 7 | 5 | 5 | 29 | 23 | a | ||
| 6 | | FC Utrecht | 53 | 34 | 13 | 14 | 7 | 52 | 41 | +11 | 25 | 17 | 6 | 7 | 4 | 27 | 25 | 28 | 17 | 7 | 7 | 3 | 25 | 16 | a | ||
| 7 |  | FC Groningen | 50 | 34 | 14 | 8 | 12 | 40 | 37 | +3 | 27 | 17 | 7 | 6 | 4 | 17 | 13 | 23 | 17 | 7 | 2 | 8 | 23 | 24 | a | ||
| 8 |  | Sparta Rotterdam | 47 | 34 | 13 | 8 | 13 | 49 | 48 | +1 | 22 | 17 | 6 | 4 | 7 | 30 | 27 | 25 | 17 | 7 | 4 | 6 | 19 | 21 | a | ||
| 9 |  | Heracles Almelo | 44 | 34 | 12 | 8 | 14 | 42 | 53 | -11 | 28 | 17 | 8 | 4 | 5 | 29 | 16 | 16 | 17 | 4 | 4 | 9 | 13 | 37 | a | ||
| 10 |  | FC Twente | 41 | 34 | 10 | 11 | 13 | 48 | 50 | -2 | 18 | 17 | 4 | 6 | 7 | 23 | 25 | 23 | 17 | 6 | 5 | 6 | 25 | 25 | a | ||
| 11 |  | Fortuna Sittard | 41 | 34 | 12 | 5 | 17 | 50 | 58 | -8 | 18 | 17 | 5 | 3 | 9 | 27 | 33 | 23 | 17 | 7 | 2 | 8 | 23 | 25 | a | ||
| 12 |  | Heerenveen | 39 | 34 | 9 | 12 | 13 | 43 | 49 | -6 | 23 | 17 | 6 | 5 | 6 | 22 | 18 | 16 | 17 | 3 | 7 | 7 | 21 | 31 | a | ||
| 13 |  | Zwolle | 38 | 34 | 9 | 11 | 14 | 44 | 53 | -9 | 24 | 17 | 6 | 6 | 5 | 19 | 18 | 14 | 17 | 3 | 5 | 9 | 25 | 35 | a | ||
| 14 |  | Willem II | 31 | 34 | 8 | 7 | 19 | 40 | 68 | -28 | 20 | 17 | 6 | 2 | 9 | 22 | 33 | 11 | 17 | 2 | 5 | 10 | 18 | 35 | a | ||
| 15 |  | RKC Waalwijk | 30 | 34 | 7 | 9 | 18 | 33 | 55 | -22 | 19 | 17 | 5 | 4 | 8 | 21 | 25 | 11 | 17 | 2 | 5 | 10 | 12 | 30 | a | ||
| 16 |  | FC Emmen | 30 | 34 | 7 | 9 | 18 | 40 | 68 | -28 | 16 | 17 | 4 | 4 | 9 | 26 | 41 | 14 | 17 | 3 | 5 | 9 | 14 | 27 | a | ||
| 17 |  | VVV-Venlo | 23 | 34 | 6 | 5 | 23 | 43 | 91 | -48 | 13 | 17 | 3 | 4 | 10 | 20 | 46 | 10 | 17 | 3 | 1 | 13 | 23 | 45 | a | ||
| 18 |  | ADO Den Haag | 22 | 34 | 4 | 10 | 20 | 29 | 76 | -47 | 9 | 17 | 1 | 6 | 10 | 17 | 38 | 13 | 17 | 3 | 4 | 10 | 12 | 38 | a |
 | Champions League |
| Champions League - 2. Vorrunde |
| Europa League Play-off |
| Conference League - 3. Qualifikationsrunde |
| Play-off Europa League |
| Play-off Relegation |
| Relegation |
